Get a baseline DXA scan
So I then knew for sure it was the Wegovy that caused this." - WasabiArtistic4675 Some reported their palpitations were intermittent but clearly connected to injection days: "Its sporadic and there is certainly a correlation with the medicine because they get worse every time I inject it." - anonymous (deleted user) And a few describe more severe reactions, including episodes of tachycardia or needing hospital care: "My husband increased doses to 2
The molecule does not activate a novel pathway its distinctiveness lies in greater bioavailability, not in different signaling
MK-677 is a non-peptide spiropiperidine previously shown to be functionally and mechanistically indistinguishable in vitro and in vivo from the potent peptide GHS GHRP-6.1 MK-677 has been found to elevate GH levels, as well as IGF-I and cortisol levels, in dogs after oral administration:6 this stimulatory effect appears to depend on the presence of an intact pituitary.7 Previous studies in humans demonstrated that daily oral administration of MK-677 in healthy older adults,8 GH-deficient adults9 for 4 weeks, and GH-deficient children10 for 7 days increased serum GH, IGF-I, and IGF binding protein (IGFBP)-3 concentrations
This stretches pain receptors and is a very common cause of burning
It shrugs off the enzyme DPP-4 and grabs onto albumin in the blood, and those two tricks stretch its half-life to roughly a week
