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We collected the feces of db/db mice after TZP intervention to perform microbial 16s rRNA sequencing and found that the diversity of intestinal microflora in the Tirzepatide group was significantly reduced and the species composition was significantly altered compared to the solvent control group

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500 l of chloroform was added to the cells and the suspension was vortexed for 1 hour at 4 C

That made us feel very comfortable and confident