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None of GHK-Cu, BPC-157, or TB-500 has an approved human indication, and the GLOW combination specifically has no clinical trial establishing safety or efficacy in humans

10.1111/j.1460-9568.2005.04426.x 81

Indeed, a study published in Diabetes, Obesity and Metabolism found that people regained two-thirds of their original weight a year after stopping the drug semaglutide

In this excellent data story, Nesta's resident data journalist Charlie Meyrick sets out how weight loss drugs work, explores the impact and cost of using them to treat obesity, and examines the role they should play in the wider health system