Finally, the authors report that, following DHA uptake, NAD + depletion by PARP activation contributes to the inhibition of glycolysis (and potentially to the stimulation of oxidative PPP flux)
Nedd8 targets ubiquitin ligase Smurf2 for neddylation and promote its degradation
This combination may interact with chemotherapy medicines (like doxorubicin and cisplatin), aluminum-containing antacids (like maalox), estrogen-containing medications (like estradiol), protease inhibitors (like indinavir), statins (like atorvastatin) and anticoagulants (like warfarin)
J Food Qual 2022:5135880 Hsu WH, Qiu WL, Tsao SM, Tseng AJ, Lu MK, Hua WJ, Lin TY (2020) Effects of WSG, a polysaccharide from Ganoderma lucidum , on suppressing cell growth and mobility of lung cancer
Timeline has an unfair advantage since it's owned by the Swiss company that developed Mitopure, the branded urolithin A that's been most widely studied
10.1038/nrneph.2014.185 96 KramannR.GoettschC.WongboonsinJ.IwataH.SchneiderR