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GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) are incretin hormones produced by specialised L-cells and K-cells in the gut after eating
Additionally, while other conjugates exhibited decreased inhibition of prostaglandin E2 synthesis, hexahydrocurcuminol is biologically inert (115)
As tirzepatide gradually clears from your system over 3 to 4 weeks, you may experience a transition period during which side effects evolve and your body readjusts to functioning without the medication's effects
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Endotext (updated 12 Feb 2000)