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For example, the FDA has approved several GLP-1 medications for chronic weight management, including the new Wegovy (semaglutide) pill as well as the injectable drugs Wegovy and Zepbound (tirzepatide)

This dual mechanismrapid weight loss combined with potential direct effects on gallbladder functionmay explain the observed association between GLP-1 therapy and gallstone risk

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These treatments activate receptors involved in appetite, insulin response, and glucose control metabolism

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