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In a newly-announced Phase 3 clinical trial, the triple receptor agonist drug retatrutide delivered some of the most dramatic weight loss results seen to date

The endocrinologist or prescribing physician manages the indication for treatment, dose escalation, metabolic response, systemic side effects and long-term safety

If you take GLP-1 and GIP with insulin or an insulin GLP-1 and GIP (eg, a sulfonylurea), blood glucose should be monitored very closely, multiple times a day

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This period is often when your treatment plan calls for a dose increase

Although tirzepatide gradually leaves your bloodstream during this time, its effects on appetite, blood sugar, and metabolism may continue for several weeks